Signaling through HLA-DR induces PKCβ-dependent B cell death outside rafts
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چکیده
منابع مشابه
Cutting edge: B cell antigen receptor signaling occurs outside lipid rafts in immature B cells.
B cell Ag receptor (BCR) signaling changes dramatically during B cell development, resulting in activation in mature B cells and apoptosis, receptor editing, or anergy in immature B cells. BCR signaling in mature B cells was shown to be initiated by the translocation of the BCR into cholesterol- and sphingolipid-enriched membrane microdomains that include the Src family kinase Lyn and exclude t...
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ژورنال
عنوان ژورنال: European Journal of Immunology
سال: 2003
ISSN: 0014-2980,1521-4141
DOI: 10.1002/eji.200323351